血尿酸及胆红素联合检测对冠心病的临床价值

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目的分析冠心病患者接受血尿酸检测和胆红素检测对临床确诊的具体作用。方法 110例冠心病患者作为观察组,110例健康体检人员作为对照组,两组均进行血尿酸和胆红素检测,对比两组研究对象及不同冠心病分型患者的检测结果。结果观察组血尿酸水平(382.60±62.74)μmol/L高于对照组(263.84±52.38)μmol/L,差异有统计学意义(P<0.05);对照组总胆红素水平(14.88±1.38)μmol/L高于观察组(9.76±1.13)μmol/L,差异有统计学意义(P<0.05);对照组直接胆红素水平(3.79±0.67)μmol/L高于观察组(2.13±0.35)μmol/L,差异有统计学意义(P<0.05);对照组间接胆红素水平(10.26±0.85)μmol/L高于观察组(7.32±0.55)μmol/L,差异有统计学意义(P<0.05)。观察组110例患者中,稳定型心绞痛38例、不稳定型心绞痛37例、心肌梗死35例,三种不同分型冠心病患者的血尿酸及胆红素水平比较,差异均具有统计学意义(P<0.05)。结论与健康人相比,冠心病患者的胆红素和血尿酸检测结果异常,对于疑似冠心病患者,临床中有必要为患者进行相关检测,为冠心病患者的临床诊断提供更加科学的依据。 Objective To analyze the specific role of serum uric acid and bilirubin in clinical diagnosis of patients with coronary heart disease. Methods One hundred and ten patients with coronary heart disease were selected as observation group and 110 healthy subjects as control group. Serum uric acid and bilirubin were measured in both groups, and the results of two groups of patients and different types of coronary heart disease were compared. Results The level of serum uric acid (382.60 ± 62.74) μmol / L in the observation group was significantly higher than that in the control group (263.84 ± 52.38 μmol / L) (P <0.05). The total bilirubin level in the control group (14.88 ± 1.38) μmol / L was higher than that of the observation group (9.76 ± 1.13) μmol / L, the difference was statistically significant (P <0.05) ) μmol / L (P <0.05). The level of indirect bilirubin in the control group (10.26 ± 0.85) μmol / L was significantly higher than that in the observation group (7.32 ± 0.55) μmol / L P <0.05). Among the 110 patients in observation group, there were 38 cases of stable angina pectoris, 37 cases of unstable angina pectoris and 35 cases of myocardial infarction. The levels of serum uric acid and bilirubin in three different types of patients with coronary heart disease were significantly different P <0.05). Conclusion Compared with healthy controls, the results of bilirubin and serum uric acid in patients with coronary heart disease are abnormal. For patients suspected of having coronary heart disease, it is necessary to conduct relevant tests in patients with coronary heart disease and provide a more scientific basis for the clinical diagnosis of patients with coronary heart disease.
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