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目的:探讨CD147与脑梗死及其进展型之间的关系。方法:将脑梗塞患者分为进展型脑梗死组和非进展型脑梗死组,对两组第一次院时1d、3d、5d和7d血清CD147进行比较。结果:进展型脑梗死组和非进展型脑梗死组患者各时间点CD147均高于对照组。进展型脑梗死组和非进展型脑梗死组患者在入院后3d、5d和7d比较,有差异。进展型脑梗死组CD147高于非进展型脑梗死组患者。结论:CD147在脑梗塞患者表达升高,并可能成为进展型脑梗塞的检验预测靶点。
Objective: To investigate the relationship between CD147 and cerebral infarction and its progression. Methods: The patients with cerebral infarction were divided into progressive cerebral infarction group and non-progressing cerebral infarction group. The serum CD147 level of the first hospital on the 1st, 3rd, 5th, and 7th day of hospital was compared. Results: CD147 in patients with progressive cerebral infarction and non-progressive cerebral infarction were higher than those in control group at each time point. Differences were found in the patients with progressive cerebral infarction and non-progressive cerebral infarction at 3d, 5d and 7d after admission. Progressive cerebral infarction group CD147 higher than non-progressing cerebral infarction patients. Conclusion: The expression of CD147 is increased in patients with cerebral infarction, and may be the target of the test for predicting progressive cerebral infarction.