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目的:探讨高龄初产妇并发重度子痫前期对母儿预后的影响。方法:以该院2001年4月～2008年4月收治的重度子痫前期单胎妊娠年龄≥35岁的初产孕妇26例为观察组,同期重度子痫前期单胎妊娠年龄<35岁的初产孕妇107例为对照组,对两组患者资料进行回顾性分析,比较两组孕妇及围生儿的最终结局。结果:观察组内科合并症发生率较对照组高,差异有统计学意义(P<0.05),产后出血、胎盘早剥发生率两组比较差异无统计学意义(P>0.05)。观察组低体重儿出生率、新生儿窒息和围产儿死亡率较对照组高,差异有统计学意义(P<0.05)。结论:高龄初产妇并发重度子痫前期对母儿危害大,应加强产前监护,适时终止妊娠,以改善母儿预后。
Objective: To investigate the impact of early primipara in severe preeclampsia on the prognosis of maternal and infant. Methods: A total of 26 cases of primiparous women with severe preeclampsia ≥35 years of age who were admitted to our hospital from April 2001 to April 2008 were enrolled in this study. The incidence of singleton pregnancies in the severe preeclampsia was <35 years 107 primiparous pregnant women as the control group, the data of two groups were retrospectively analyzed, the final outcome of the two groups of pregnant women and perinatal children were compared. Results: The incidence of medical comorbidity in the observation group was higher than that in the control group (P <0.05). There was no significant difference in the incidence of postpartum hemorrhage and placental abruption between the two groups (P> 0.05). The birth rate, neonatal asphyxia and perinatal mortality in observation group were higher than those in control group, with significant difference (P <0.05). Conclusion: The early primipara of pregnant women with severe preeclampsia is more harmful to the mother and child. Prenatal care should be strengthened to terminate the pregnancy timely to improve the prognosis of the mother and child.