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目的观察氨茶碱联合纳洛酮治疗早产儿原发性呼吸暂停的治疗效果。方法原发性呼吸暂停早产儿87例随机分为两组,对照组42例应用氨茶碱治疗;治疗组45例应用氨茶碱联合纳洛酮治疗。比较总有效率及不良反应。结果治疗组总有效率95.6%,对照组78.6%,差异有统计学意义(χ2=5.67,P<0.05),无不良反应。结论氨茶碱联合纳洛酮治疗早产儿原发性呼吸暂停安全、有效。
Objective To observe the therapeutic effect of aminophylline combined with naloxone in the treatment of premature infants with primary apnea. Methods 87 cases of premature infants with primary apnea were randomly divided into two groups, 42 cases in the control group were treated with aminophylline; 45 cases in the treatment group were treated with aminophylline and naloxone. Compare the total efficiency and adverse reactions. Results The total effective rate was 95.6% in the treatment group and 78.6% in the control group, the difference was statistically significant (χ2 = 5.67, P <0.05), no adverse reactions. Conclusion Aminophylline combined with naloxone in the treatment of premature infants with primary apnea is safe and effective.