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目的探讨多发性骨髓瘤患者外周血成分变化对ABO血型鉴定的影响,为正确鉴定多发性骨髓瘤患者ABO血型寻求更为合理的方法。方法 40名MM患者用常规方法做ABO血型正反定型;对正反定型不符者,采用消除红细胞自身凝集、不规则抗体检查、A1抗原检测、直接抗球蛋白试验、吸收放散试验、唾液血型物质检测等方法,以正确进行ABO血型鉴定;对多发性骨髓瘤患者实验室检查结果与血型鉴定情况做统计学分析。结果 40名MM患者中30名患者ABO血型鉴定正反定型不符。结论多发性骨髓瘤患者外周血成分变化严重影响血型的正确鉴定,应进行多种血型血清学试验,综合分析,以确保血型的准确性和输血的安全性。
Objective To investigate the effect of peripheral blood components changes on the identification of ABO blood group in patients with multiple myeloma and to seek a more reasonable method for the correct identification of ABO blood group in patients with multiple myeloma. Methods Forty MM patients underwent ABO blood type positive and negative stereotypes by the conventional method. For positive and negative type discrepancy patients, self-agglutination of erythrocytes, irregular antibody test, A1 antigen test, direct antiglobulin test, absorption and emission test, saliva blood type substance Detection and other methods to correctly ABO blood group identification; multiple myeloma laboratory test results and blood type identification to do statistical analysis. Results 30 patients in 40 MM patients ABO blood group identification positive and negative stereotypes do not match. Conclusion The changes of peripheral blood components in patients with multiple myeloma seriously affect the correct identification of blood type. Various blood group serological tests should be conducted and analyzed comprehensively to ensure the accuracy of blood type and blood transfusion safety.