胎粪吸入综合征(meconium aspiration syndrome,MAS)为新生儿特有疾病,是指胎儿在宫内或娩出时吸入被胎粪污染的羊水而引起的呼吸道机械性阻塞、肺组织化学性炎症及一系列全身症状的临床综合征,主要发生于足月儿及过期产儿,是导致新生儿呼吸衰竭和死亡的主要原因之一,病死率达7.0%~15.8%~([1]),对新生儿身体健康和生命安全危害极大。本研究就MAS的发病机制、诊断及治疗方面的研究进展作一综述,为其 Meconium aspiration syndrome (MAS) is a specific disease of the newborn and refers to mechanical obstruction of the respiratory tract caused by inhalation of meconium aspiration syndrome (amniotic fluid contaminated amniotic fluid during intrauterine or delivery), chemical inflammation of the lung tissue and a series of The clinical symptoms of systemic symptoms mainly occur in term infants and expired infants, which are one of the major causes of neonatal respiratory failure and death with a mortality rate of 7.0% -15.8% ~ ([1]). Neonatal Health and safety of life are extremely dangerous. This review summarizes the research progress on the pathogenesis, diagnosis and treatment of MAS.