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作者介绍30多年所观察174例再生障碍性贫血(aplastic anemia,AA)的经验。着重介绍该病的经过、预后因素、治疗与转归。所有病例均有全血细胞减少,并在疾病的过程中出现骨髓增生低下。男76例,女98例。38例有药物接触史。43例单纯用支持疗法,其中达到血液学缓解和部分缓解者占46%,36例单纯用康复龙(oxymetholone)或与皮质激素合用,50%获得血液学改善;18例予以其它各种雄激素与皮质激素合用,61%有部分血液学缓解;76例单独用皮质激素,34%获得血液学缓解。上述部分病例血液学缓解短暂,对预后无影响。比较其
The authors describe the experience of 174 cases of aplastic anemia (AA) observed over 30 years. Emphasis will be given on the course of the disease, prognostic factors, treatment and outcome. All cases had pancytopenia and had low myeloproliferation during the disease. 76 males and 98 females. 38 cases of drug exposure history. Of the 43 patients treated with supportive therapy alone, 46% achieved hematologic remission and partial remission, 36 received oxymetholone alone or in combination with corticosteroids, and 50% achieved hematologic improvement. Eighteen patients received other androgen supplements In combination with corticosteroids, 61% had some hematologic remission; 76 received corticosteroid alone and 34% achieved hematologic remission. Some of the cases of hematological relief short-term, no effect on the prognosis. Compare it