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儿童意外摄入含铁过多的强化食品,特别是幼儿误服大量硫酸亚铁片,引起急性铁中毒,导致严重后果,甚至死亡,在儿科并非罕见。据美国统计每年有5,000例铁中毒发生,病死率为1/100,应引起临床医生的重视。最常见的急性铁中毒是由硫酸亚铁过量引起,致死量为口服200～250mg/kg元素铁,有作者报告130mg/kg元素铁即可致死。病理生理正常情况下,平均每天摄入铁约为15mg,大约10%以低铁形式在胃肠粘膜被吸收。Fe~(++)
Children accidentally intake of too much iron fortified foods, especially children accidentally take large amounts of ferrous sulfate tablets, causing acute iron poisoning, leading to serious consequences, and even death, is not uncommon in pediatrics. According to the statistics of the United States, there are 5,000 cases of iron poisoning every year, with a case fatality rate of 1/100, which should arouse the attention of clinicians. The most common acute iron poisoning is caused by an overdose of ferrous sulphate, with a lethal dose of 200 to 250 mg / kg of elemental iron orally, with the authors reporting that 130 mg / kg of elemental iron can be fatal. Under normal pathophysiology, the average daily intake of iron is about 15 mg and about 10% is absorbed in the gastrointestinal mucosa as low iron. Fe ~ (++)