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目的研究不同年龄段反复喘息患儿临床特点及吸入激素临床控制的差异。方法 343例反复喘息患儿进行研究,抽签随机分为吸入治疗组(143例)与未吸入治疗组(200例),比较两组控制率及持续喘息率,并围绕年龄对患儿发病率及控制率进行研究。结果≤6个月、6~12个月、1~3岁、3~7岁、7~12岁临床控制率分别为68.0%、75.0%、75.9%、77.3%、45.7%,3~7岁患儿控制率最高,7~12岁患儿最低;吸入治疗组控制率79.7%,持续哮喘20.3%,未吸入组67.0%临床控制,33.0%未控制,两组控制率比较差异有统计学意义(P<0.05)。结论小儿反复喘息大多发生在7岁以内,采取吸入激素治疗效果显著,可有效防止反复喘息持续至成人期。
Objective To study the clinical features and clinical control of inhaled hormones in children with recurrent wheezing at different ages. Methods A total of 343 children with wheezing were randomly divided into two groups: control group (n = 200) and inhalation group (n = 143). The control group and sustained wheezing rate were compared between the two groups. Control rate research. Results The clinical control rates were 68.0%, 75.0%, 75.9%, 77.3%, 45.7%, 3-7 years old at 6 months, 6-12 months, 1-3 years, 3-7 years and 7-12 years old respectively The highest rate of children control, 7 to 12-year-old children in the lowest; inhalation therapy group control rate of 79.7%, sustained asthma 20.3%, 67.0% non-inhalation group clinical control, 33.0% uncontrolled, control difference between the two groups was statistically significant (P <0.05). Conclusion Most children with recurrent wheezing occurred within 7 years of age, taking inhaled corticosteroids was effective and could effectively prevent repeated wheezing until adulthood.