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目的:选取广西、云南、贵州三种产地的金樱根药材,对其根和茎样品的抗炎镇痛活性进行评价。方法:采用鼠耳肿胀法、大鼠足跖肿胀法对金樱根药材根和茎样品的抗炎活性进行比较,采用小鼠醋酸扭体法对其镇痛活性进行比较。结果:金樱根药材均可抑制鼠耳廓肿胀和小鼠扭体反应;部分金樱根药材样品对角叉菜胶致大鼠足跖肿胀表现为抑制作用。结论:金樱根药材样品具有一定的抗炎作用并且具有不同程度的镇痛作用。
OBJECTIVE: To determine the anti-inflammatory and analgesic activities of the roots and stems of Jingengen medicinal materials in Guangxi, Yunnan and Guizhou. Methods: The anti-inflammatory activity of root and stem samples of Jinying root was compared by mouse ear swelling method and rat paw edema method. The analgesic activity of mice was compared by acetic acid writhing method. Results: Allium saponins could inhibit swelling of mouse ears and writhing reaction in mice. Some samples of Jinyingen could inhibit carrageenan-induced paw edema in rats. Conclusion: Jin Ying root medicinal samples have some anti-inflammatory effects and have varying degrees of analgesic effect.