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在63只麻醉、制动、断双侧迷走神经、人工呼吸的家兔,观察了股动脉注射琥珀胆碱Sch诱发肌梭传入对延髓呼吸相关神经元自发放电的影响。结果发现:股动脉注射Sch对延髓吸气神经元的作用以兴奋为主37/56,对呼气神经元的作用以抑制为主10/17,而对非呼吸性神经元这种兴奋与抑制反应则不明显;Sch对吸气神经元的兴奋作用,一般在给药后1~2min即可达高峰,而对呼气神经元的抑制作用则发生较晚,一般在给药后2~3min达高峰;肌注布比卡因破坏肌梭后可明显降低Sch对延髓呼吸相关神经元的影响。结果提示,股动脉注射Sch诱发的肌梭传入可通过延髓呼吸中枢参与对运动性通气增强反应的调节。
Sixty-three anesthetized, braked, and bilateral vagus nerve and respira- tive rabbits were observed for the spontaneous discharge of respiratory neurons associated with medulla oblongata-Schwann cells induced by Schisandra Schwannus injection. The results showed that: Fe injection of femoral artery to the medullary inspiratory neurons mainly excited 37/56, the main inhibition of exhaled neurons 10/17, while non-respiratory neurons such excitement and inhibition The reaction is insignificant; Sch for inspiratory neurons excited role, usually in 1 ~ 2min after administration to reach the peak, while the inhibition of exhaled neurons occurs later, usually after administration of 2 ~ 3min Reaching the peak; Muscle injection of Bupivacaine can significantly reduce the impact of Sch on the medullary respiratory-related neurons after disruption of muscle spindles. The results suggest that the introduction of Schizophrenia induced by Fe in the femoral artery can be involved in the modulation of exercise-induced enhancement through the medullary respiratory center.