FDA要求氟喹诺酮类抗菌药的药品标签和用药指南对其潜在外周神经病变风险作出更强的警告。服用该类药品可能迅速发生严重神经病变且症状持久,警告仅适用于口服或注射用氟喹诺酮类制剂,目前尚不清楚用于眼睛或耳部的外用氟喹诺酮类药物与周围神经病变的发生危险相关。已获批的氟喹诺酮类药物包括左氧氟沙星、环丙沙星、莫西沙星、诺氟沙星、氧氟沙星和吉米沙星。FDA建议若患者出现周围神经病变症状应停用氟喹诺酮类药物,并更换其他非氟喹诺酮类抗菌药,除外氟喹诺酮类药物的临床获益大于其相应的风险。周围神经病变是发生在上下肢的一种神经障碍 The FDA requires fluoroquinolone antimicrobial drug labels and guidelines to give a stronger warning of the potential risk of peripheral neuropathy. Serious neuropathies and long lasting symptoms may occur with these drugs. Warnings apply only to fluoroquinolones for oral or injectable use. It is unclear whether topical fluoroquinolones or peripheral neuropathy are at risk for the eye or ear Related. Approved fluoroquinolones include levofloxacin, ciprofloxacin, moxifloxacin, norfloxacin, ofloxacin and gemifloxacin. FDA recommends that patients with peripheral neuropathy symptoms should be discontinued fluoroquinolones, and replace other non-fluoroquinolone antibacterials, except fluoroquinolones clinical benefit is greater than the corresponding risk. Peripheral neuropathy is a neurological disorder that occurs in the upper and lower extremities