国外对慢性活动性肝炎(以下简称慢活肝)主要应用免疫抑制药物治疗,常用者有肾上腺皮质激素(强的松、强的松龙、地塞米松、琥珀酰氢考的松等,以下称激素)、硫唑嘌呤、6-巯基嘌呤、青霉胺、强力新、秋水仙碱等。激素治疗病毒性肝炎的新概念是抑制迟发型免疫反应,可使胸腺萎缩、破坏和淋巴细胞的制造减少。本品可增加肝糖元,促使肌肉和骨骼的蛋白质分解,在肝内则反促使肝细胞合成蛋白质。文献报道小剂量激素能促进机体巨噬细胞吞噬作用,中、大剂量激素有抑制细胞的吞噬功能,故病人长期使用激素易发生继发感染。激素能保护 Abroad for chronic active hepatitis (hereinafter referred to as slow living liver) is mainly used immunosuppressive drug treatment, commonly used adrenal cortex hormones (prednisone, prednisolone, dexamethasone, succinyl hydrogen test cortisone, the following Hormones), azathioprine, 6-mercaptopurine, penicillamine, powerful new, colchicine and so on. The new concept of hormonal treatment of viral hepatitis is to suppress the delayed type of immune response, which can make thymus atrophy, destruction and reduction of lymphocyte production. This product can increase glycogen, muscle and bone to promote protein breakdown, the liver is against liver cells to promote protein synthesis. Reported in the literature of small doses of hormone can promote phagocytosis of macrophages, medium and large doses of hormone inhibition of phagocytic cells, so long-term use of the patient prone to secondary hormone infection. Hormone can protect