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目的:对米索前列醇不同给药方式在产后出血预防中的疗效进行观察。方法:选取从2011年1月到2014年1月收治的100位产妇,随机将所有产妇分成对照组(50)与观察组(50),对照组口服给药,观察组直肠给药,两组预防产后出血均采用米索前列醇。结果:在观察组中,有47位产妇子宫收缩效果良好,占94.00%;在对照组中,有40位产妇子宫收缩效果良好,占80.00%,观察组明显高于对照组(P<0.05)。观察组发生不良反应概率为2.00%,对照组发生不良反应概率为4.00%,两组无明显差异(P>0.05)。在产后2h与24h出血量方面,观察组明显少于对照组(P<0.05)。结论:对于产后出血的预防采取米索前列醇直肠给药方式,疗效理想,在产妇出血量以及子宫收缩方面均优于口服给药组,安全有效,具有临床应用价值。
Objective: To observe the curative effect of misoprostol on different ways of preventing postpartum hemorrhage. Methods: 100 maternal women who were admitted to our hospital from January 2011 to January 2014 were randomly divided into control group (50) and observation group (50). The control group was orally administered and the observation group received rectal administration. The two groups Prevention of postpartum hemorrhage with misoprostol. Results: In the observation group, 47 maternal uterine contractions were good, accounting for 94.00%; in the control group, 40 maternal uterine contractions were good, accounting for 80.00%, the observation group was significantly higher than the control group (P <0.05) . The probability of adverse reactions in the observation group was 2.00%, the incidence of adverse reactions in the control group was 4.00%, there was no significant difference between the two groups (P> 0.05). In the 2h and 24h postpartum hemorrhage, the observation group was significantly less than the control group (P <0.05). Conclusion: The prevention of postpartum hemorrhage with misoprostol rectal administration, the effect is ideal, in maternal blood loss and uterine contractions are superior to the oral administration group, safe and effective, with clinical value.