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目的:通过为期4周的随机对照临床实验研究观察舒缓抗敏牙膏抑制牙本质敏感的功效。方法:将80例志愿者(共809颗牙齿)随机分为2组:实验组(舒缓抗敏牙膏组)和对照组(安慰剂组)。采用Schiff冷空气敏感指数评价冷空气吹喷敏感性和视觉模拟评分法(VAS)记录探诊敏感性。并记录受试者每天牙本质敏感疼痛的主观感受VAS值。结果:实验组使用舒缓抗敏牙膏2周后,受试者每天牙本质敏感疼痛的主观感受明显减轻,并与对照组有统计学差异(P<0.05);4周后,实验组受试者每天牙本质敏感疼痛的主观感受、Schiff冷空气敏感和探诊敏感均较使用前明显减轻(P<0.05),并且改善程度优于对照组(P<0.05)。结论:使用舒缓抗敏牙膏4周后可显著改善牙本质敏感症状。
OBJECTIVE: To observe the efficacy of soothing anti-allergic toothpaste in inhibiting dentin hypersensitivity through a 4-week randomized controlled clinical trial. Methods: Eighty volunteers (809 teeth in all) were randomly divided into two groups: experimental group (anti-allergic toothpaste group) and control group (placebo group). The Schiff cold air sensitivity index was used to evaluate cold air blowout sensitivity and visual analogue scale (VAS) recording probe visit sensitivity. The subjective VAS values of dentin-sensitive pain in the subjects were recorded. Results: After 2 weeks of using anti-allergic toothpaste, the subjective sensation of dentin-sensitized pain in the experimental group was significantly reduced (P <0.05). After 4 weeks, the subjects in the experimental group The daily subjective feeling of dentin-sensitized pain, Schiff’s cold-air sensitivity and probing sensitivity were significantly lower than those before use (P <0.05), and the improvement was better than that of the control group (P <0.05). CONCLUSIONS: The use of soothing anti-allergic toothpaste can significantly improve dentine-sensing symptoms after 4 weeks.