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目的观察丹参饮联合奥美拉唑、阿莫西林、甲硝唑治疗幽门螺杆菌(HP)相关性消化性溃疡的临床疗效。方法将150例HP相关性消化性溃疡随机分为治疗组75例,对照组75例。治疗组采用丹参饮联合奥美拉唑、阿莫西林、甲硝唑治疗;对照组单用奥美拉唑、阿莫西林和甲硝唑治疗;观察二组治疗前后胃镜、HP的变化。结果治疗组在溃疡愈合、HP根除,与对照组相比差异有显著性意义(P<0.05)。结论中西医结合治疗能显著提高幽门螺杆菌感染的根除率,并且患者临床症状有明显改善。
Objective To observe the clinical efficacy of Danshen Decoction combined with omeprazole, amoxicillin and metronidazole in the treatment of peptic ulcer associated with Helicobacter pylori (HP). Methods 150 cases of HP-related peptic ulcer were randomly divided into treatment group 75 cases, control group 75 cases. The treatment group was treated with Salvia miltiorrhiza combined with omeprazole, amoxicillin and metronidazole. The control group was treated with omeprazole, amoxicillin and metronidazole alone. The changes of gastroscope and HP in the two groups were observed before and after treatment. Results In the treatment group, ulcer healing and HP eradication had significant differences compared with the control group (P <0.05). Conclusion The combination of traditional Chinese and Western medicine can significantly improve the eradication rate of Helicobacter pylori infection, and patients with clinical symptoms improved significantly.