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目的:探究色素胃镜在食管早癌及异型增生诊断中的应用价值。方法:对我院170例胃镜检查发现可疑食管黏膜病变者,用2.0%卢戈氏碘液染色后取活检,结合病理分析,探讨内镜下病变部位碘染色改变与活检病理结果的关系。结果:170例患者中有139例呈现碘不染色,活检病理诊断食管癌36例,异型增生39例;碘淡染及碘不染色者仅有6例异型增生,余均为慢性炎症。内镜下碘不染区异型增生及食管癌共75例,检出率高于碘淡染及碘正常染色区(χ2=16.283,P<0.05)。结论:色素胃镜能鉴别食管黏膜病变,指导活检可提高食管早癌及异型增生的检出率。
Objective: To explore the value of pigmented gastroscopy in the diagnosis of esophageal cancer and dysplasia. Methods: 170 cases of suspected esophageal mucosal lesions detected by gastroscopy in our hospital were stained with 2.0% Lugol’s iodine solution and biopsied. Combined with pathological analysis, the relationship between the changes of endoscopic iodine staining and biopsy results was analyzed. Results: Of the 170 patients, 139 cases showed iodine non-staining, biopsy pathological diagnosis of esophageal cancer in 36 cases, dysplasia 39 cases; iodine light staining and iodine non-staining only 6 cases of dysplasia, the remaining were chronic inflammation. There were 75 cases of dysplasia and esophageal carcinoma in iodine-exposed area under endoscopy, the detection rate was higher than that of iodine-light-stained and iodine-stained area (χ2 = 16.283, P <0.05). Conclusion: Pigmented gastroscope can identify esophageal mucosal lesions, guide biopsy can improve the detection rate of esophageal cancer and dysplasia.