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C反应蛋白浓度的基线水平是人体心血管疾病易感性的指标并有40%～50%的遗传性。本实验旨在研究C反应蛋白(C reactive protein,CRP)+1059与白介素-1B(interleukin-1B,IL-1B)+3954基因多态性联合作用对CRP基线水平的影响及其对心血管疾病的影响。材料和方法取336位芬兰高加索民族
Baseline C-reactive protein levels are indicators of susceptibility to cardiovascular disease in humans and are 40% to 50% heritable. The purpose of this study was to investigate the effect of combined effect of C reactive protein (CRP) +1059 and interleukin-1B (IL-1B) +3954 gene polymorphism on CRP baseline levels and its effect on cardiovascular diseases Impact. Materials and methods Take 336 Finnish Caucasians