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目的 观察孤儿受体酪氨酸激酶 (Ret)在成年大鼠腰段脊髓和背根节中的分布 ,探讨胶质细胞源性神经营养因子 (GDNF)对大鼠脊髓和背根节神经元的作用。 方法 采用Ret抗体免疫组织化学ABC法。 结果 Ret免疫反应存在于成年大鼠腰段脊髓神经元和背根节神经元中。 结论 Ret在大鼠腰段脊髓和背根节神经元中有一定的分布
Objective To observe the distribution of orphan receptor tyrosine kinase (Ret) in the lumbar spinal cord and dorsal root ganglion in adult rats and to investigate the effect of GDNF on the neurons in the spinal cord and dorsal root ganglion effect. Methods Ret antibody immunohistochemical ABC method. Results Ret immune response exists in adult lumbar spinal cord neurons and dorsal root ganglion neurons. Conclusion Ret has certain distribution in the lumbar spinal cord and dorsal root ganglion neurons in rats