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目的研讨不稳定型心绞痛(UAP)患者接受氯吡格雷治疗的临床作用。方法从我院2013年12月-2016年1月选取420例UAP患者参与研究试验,按随机非盲法实行组别划分,Ⅰ组210例接受常规基础治疗,Ⅱ组210例在上述治疗下接受氯吡格雷服用,评估该两种治疗方案在临床上的实施效果。结果Ⅱ组患者接受方案给药后,取得了91.4%的总有效率,相比Ⅰ组的总有效率(70.5%)显著提高,数据满足(P<0.05),统计学成立。24h动态心电图显示,Ⅱ组的缺血次数、缺血总时间相比Ⅰ组均显著减少或缩短,数据满足(P<0.05),统计学成立。两组均顺利完成试验治疗,未见严重性副反应产生。结论对UAP患者实施氯吡格雷治疗,可安全、有效缓解患者的症状病情,值得推荐。
Objective To investigate the clinical effect of clopidogrel in patients with unstable angina pectoris (UAP). Methods From December 2013 to January 2016, 420 UAP patients in our hospital were enrolled in the study. Randomized non-blinded method was used to divide the patients into two groups. Group Ⅰ (210 cases) received routine basic treatment, and group Ⅱ (210 cases) received the above treatment Clopidogrel taken to assess the efficacy of the two treatment options in clinical practice. Results The total effective rate of 91.4% in group Ⅱ was significantly higher than that in group Ⅰ (70.5%). The data met (P <0.05), and the statistics was established. Holter 24h electrocardiogram showed that the number of ischemia and the total time of ischemia in group Ⅱ were significantly reduced or shortened compared with that in group Ⅰ, and the data were satisfactory (P <0.05). Statistics was established. Two groups were successfully completed trial treatment, no serious side effects. Conclusion Clopidogrel treatment in patients with UAP can be safe and effective in alleviating the symptoms of patients with disease, it is recommended.