目的利用成簇的规律间隔的短回文重复序列(clustered regularly interspaced short palindromic repeats,CRISPR)/常间回文重复序列丛集关联蛋白系统(associated proteins,Cas)编辑纤连蛋白(fibronectin)基因抑制其可变剪接片段基因外显子A(extra domain A, EDA),并观察对腺样囊性癌(adeno
目的研究穿膜肽纳米类脂质体包载利多卡因(lidocaine hydrochloride loaded transactivator of transcription peptide conjugated nano-niosome,LID-TAT-N)在动物体内外透皮情况及其表面麻醉效果,为研制新型口腔表面麻醉剂提供依据。方法制备LID-TAT-N,传统脂质体包载利多卡因(lidocaine hyd