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目的通过居民头发微量元素检测,了解贵州省敦寨尿石症高发相关因素,调查其原因。方法采用硝酸:高氯酸(9∶1)消化液进行样品消解,用火焰原子吸收光谱法(FAAS)测定了尿石症高发区中游、上游地区居民头发中Fe、Zn、Cu、Ca、Mg等微量元素含量。结果当地患者比正常人Fe偏高(P<0.05),中游地区患者Ca、Mg偏低(P<0.05),上游地区患者比正常人Zn、Cu偏高(P<0.05)。与国内正常参考均值比较,该地区患者头发Fe高;中游地区发中Cu、Ca、Mg偏低,Zn偏高(P<0.05)。上游地区发中Zn偏低(P<0.05)。结论头发中某些微量元素含量异常与尿石症发病率相关,与水质,生活环境和饮食习惯有很大关系。
Objective To investigate the causes of high incidence of urolithiasis in Dunzhai, Guizhou province by detecting the trace elements in hair of residents. Methods The samples were digested with nitric acid and perchloric acid (9:1), and the contents of Fe, Zn, Cu, Ca and Mg in the hair of residents in the middle and upper reaches of urolithiasis were determined by flame atomic absorption spectrometry (FAAS) Such as trace element content. Results The local patients were higher than that of normal people (P <0.05). The Ca and Mg levels in the middle reaches were lower (P <0.05). The patients in the upper reaches were higher than the normal people (P <0.05). Compared with the normal reference value in the country, the Fe patients in this area had high hair. In the middle reaches of the hair, Cu, Ca and Mg were low and Zn was higher (P <0.05). Zn in the upstream area was lower (P <0.05). Conclusion The abnormal hair content of some trace elements associated with the incidence of urolithiasis, and water quality, living environment and eating habits have a great relationship.