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目的探讨严重急性呼吸综合征(severeacuterespiratorysyndrome,SARS)恢复期患者的影像学表现特点,及其与其他实验室检查、肺功能检查的关系。方法对100例出院约2个月的SARS患者行胸部高分辨CT检查,并有65例同时行实验室检查,91例行肺功能检查。结果49例(49.0%,49/100)患者的CT仍有异常表现,以磨玻璃样病变(95.9%,47/49)和细小网格状病变(59.2%,29/49)最为常见。按CT表现程度分组后,各组间淋巴细胞计数、CD4细胞计数的均数没有统计学差异(P>0.01);2和3级患者通过单次呼气弥散法测定弥散功能占预计值的百分比(diffusingcapacityforcarbonmonoxide,DLCO%)低于0级患者(P<0.01)。结论SARS患者恢复期与病中的影像学表现有所不同,而高分辨CT能在一定程度上反映弥散功能。
Objective To investigate the imaging characteristics of patients with convalescent severe acute respiratory syndrome (SARS) and its relationship with other laboratory tests and pulmonary function tests. Methods 100 cases of SARS discharged from hospital for about 2 months were examined by high-resolution chest CT. There were 65 concurrent laboratory tests and 91 pulmonary function tests. Results The CT findings of 49 patients (49.0%, 49/100) were still abnormal. The most commonly seen lesions were vitreous lesions (95.9%, 47/49) and small grid disease (59.2%, 29/49). According to the degree of CT grouping, there was no significant difference in the mean of lymphocyte count and CD4 count between groups (P> 0.01). The percentage of diffusion function to the predicted value was determined by single breath diffusion in grade 2 and 3 patients (diffusingcapacityforcarbonmonoxide, DLCO%) was lower than level 0 (P <0.01). Conclusion The imaging findings of SARS patients during convalescence and disease are different, while high-resolution CT can reflect the diffuse function to a certain extent.