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CD44是属于黏附分子家族的跨膜糖蛋白,具有激活淋巴细胞、参与信号传递、促进细胞黏附等多种生物学功能。CD44的异常表达与肺癌的生长、发展预后及影像学表现关系密切,本文就CD44与肺癌的关系作一综述。
CD44 is a transmembrane glycoprotein belonging to the family of adhesion molecules, which has many biological functions such as activating lymphocytes, participating in signal transmission and promoting cell adhesion. The abnormal expression of CD44 is closely related to the growth, prognosis and imaging manifestations of lung cancer. This review summarizes the relationship between CD44 and lung cancer.