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目的总结带放射性粒子食管支架应用于食管恶性狭窄治疗的效果。方法将食管恶性狭窄的患者分成两组,以带放射性粒子食管支架治疗的为观察组80例,以传统食管自膨式支架治疗的为对照组30例。在导管室行操作,行常规食管镜检查,通过食管镜监视将支架导丝经过狭窄段后至胃内,通过导丝置入传统食管支架或带放射性125-I粒子食管支架,并超过狭窄段5cm,结束操作。结果两组患者治疗后患者的吞咽困难症状均较治疗前有所缓解,支架释放均获成功。在吞咽困难方面,带放射性粒子食管支架短期疗效明显优于传统食管支架。在狭窄率方面,带放射性粒子食管支架优于常规传统食管支架。带放射性粒子食管支架治疗后生存期(19.1±3.1)个月,传统食管支架组治疗后生存期平均(8.2±1.5)个月,两组患者在治疗后生存期方面的差异有统计学意义(P<0.05)。结论放射性粒子食管支架对食管恶性狭窄是一种行之有效的方法 。
Objective To summarize the effect of radioactive esophageal stent in the treatment of malignant esophageal stenosis. Methods The patients with malignant esophageal stenosis were divided into two groups, 80 cases in observation group with radioactive particle esophageal stent and 30 cases in control group with traditional esophageal self-expanding stent. Conducted in the catheter room line routine esophagoscopy, esophagoscopy through the stent guide wire through the narrow segment to the stomach, through the guide wire into the traditional esophageal stent or radioactive 125-I particle esophageal stent, and beyond the narrow segment 5cm, the end of the operation. Results After treatment, the symptoms of dysphagia in both groups were alleviated compared with those before treatment, and the stent release was successful. In terms of dysphagia, short-term efficacy of radioactive esophageal stent is significantly better than traditional esophageal stent. In terms of stenosis, esophageal stent with radioactive particles is superior to conventional esophageal stent. Survival after radioactive particle esophageal stent treatment was (19.1 ± 3.1) months, and the average survival time was 8.2 ± 1.5 months in the traditional esophageal stent group. There was significant difference in the survival time between the two groups after treatment P <0.05). Conclusion Radioactive particle esophageal stent is an effective method for malignant esophageal stenosis.