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应用抗乙肝特异胎盘转移因子治疗慢性乙型肝炎28例。结果发现抗乙肝特异胎盘转移因子治疗组的HBeAg、HBV-DNA阴转率及抗HBe阳转率在治疗结束时分别为53.6%、50.0%和42.9%,均显著高于正常胎盘转移因子治疗组(9.1%,P<0.05)和空白对照组(6.3%,P<0.01);随访3个月均为46.2%,均显著高于空白对照组(8.7%,P<0.01)。正常胎盘转移因子治疗组和猪苓多糖加乙肝疫苗治疗组与空白对照组相比均无显著性差异(P>0.05)。提示抗乙肝特异胎盘转移因子是一种有效、价廉、使用方便的抗乙型肝炎病毒药物。
Treatment of Chronic Hepatitis B with Anti - hepatitis B Specific Placenta Transfer Factor in 28 Cases. The results showed that HBeAg, HBV-DNA negative rate and anti-HBe positive rate were 53.6%, 50.0% and 42.9% respectively at the end of treatment, which were significantly higher than that of normal placenta Transfer factor treatment group (9.1%, P <0.05) and blank control group (6.3%, P <0.01); follow-up of 3 months were 46.2%, were significantly higher than the blank control Group (8.7%, P <0.01). There was no significant difference between the normal placenta transfer factor treatment group and the Polyporus umbellatus polysaccharide plus hepatitis B vaccine treatment group and the blank control group (P> 0.05). Prompt anti-hepatitis B specific placental transfer factor is an effective, inexpensive, easy to use anti-hepatitis B virus drugs.