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应用二甲双胍干预治疗葡萄糖耐量减低(IGT)患者,分析探讨其临床应用价值。方法:选择100例临床确诊的IGT患者,随机分为二组,对照组47例,予以锻炼,饮食控制等生活方式干预。二甲双胍组在上述锻炼、生活方式干预基础上应用二甲双胍250mg每日3次,持续3个月后,二甲双胍组较对照组糖尿病发病率明显下降,同时体重指数(BMI)血脂(TC、LDL-C)等方面较对照组明显下降,差异有统计学意义(P<0.05)。
The application of metformin intervention in patients with impaired glucose tolerance (IGT), analysis and discussion of its clinical value. Methods: One hundred patients with clinically diagnosed IGT were selected and randomly divided into two groups. The control group received 47 lifestyle interventions such as exercise and diet control. Metformin group was given metformin 250mg three times a day for 3 months on the basis of exercise and lifestyle intervention. The incidence of diabetes mellitus was significantly decreased in the metformin group as compared with that in the control group, meanwhile, body mass index (BMI), lipids (TC, LDL-C) Compared with the control group decreased significantly, the difference was statistically significant (P <0.05).