【摘 要】
：
目的 探讨贵阳市50岁及以上体检人群中骨质疏松症(OP)的检出率和影响因素.方法 选取贵阳市年龄≥50岁的男性(n=1209)和自然停经超过12个月(绝经后)女性(n=838)健康体检者,收集年龄、性别、血压、身高、体质量、体质量指数(BMI)等一般情况;抽取被检者晨间空腹静脉血5 mL,采用全自动生化分析仪检测总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、尿酸(SUA)、同型半胱氨酸(Hcy)等生化指标;采用双能X线骨密度仪(DXA)检测被检者的
【机 构】
：
贵州医科大学 公共卫生学院 预防医学与妇幼保健学系, 贵州 贵阳 550025;贵州医科大学附属医院 健康管理中心, 贵州 贵阳 550004;贵州医科大学 公共卫生学院 预防医学与妇幼保健学系, 贵
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目的 探讨贵阳市50岁及以上体检人群中骨质疏松症(OP)的检出率和影响因素.方法 选取贵阳市年龄≥50岁的男性(n=1209)和自然停经超过12个月(绝经后)女性(n=838)健康体检者,收集年龄、性别、血压、身高、体质量、体质量指数(BMI)等一般情况;抽取被检者晨间空腹静脉血5 mL,采用全自动生化分析仪检测总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、尿酸(SUA)、同型半胱氨酸(Hcy)等生化指标;采用双能X线骨密度仪(DXA)检测被检者的骨密度(BMD)并分级(正常BMD、骨量减少及OP);采用无序多分类logistic回归分析健康体检者发生OP的影响因素.结果 绝经后中老年女性OP检出率高于中老年男性(χ2=208.637,P<0.05),年龄≥70岁组健康体检者OP检出率高于年龄50～59岁组和60～69岁组(χ2=63.698,P<0.05);骨量减少组和OP组被检者身高、体质量、BMI、舒张压、TC、TG、SUA、HDL-C及LDL-C水平比较,差异均有统计学意义(P<0.05);logistic回归分析结果显示,年龄、舒张压(OR=1.073、1.020,P<0.05)是被检者OP发生的危险因素,体质量和SUA(OR=0.728、0.998,P<0.05)是OP的保护因素.结论 贵阳市50岁及以上体检人群中绝经后女性OP检出率高于男性,年龄及舒张压是该人群OP发生的危险因素,尿酸水平及体质量是OP的保护因素.
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