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目的 为探讨钼靶X线和超声联合诊断在鉴别乳腺良恶性疾病中的应用价值。方法 对148例乳腺疾病患者 (其中乳腺癌53例 ,乳腺良性病变95例 )作钼靶X线和超声联合诊断 ,并与手术病理诊断对照。结果 53例乳腺癌经联合诊断有46例明确为恶性 ,确诊率较单独应用钼靶X线或超声检查 (分别只有33例和29例 )显著为高(P<0.01) ;联合诊断只有5例未能明确定性 ,未定性率也较单独应用钼靶X线或超声检查 (分别有17例和15例 )显著为低 (P<0.05) ;联合诊断只有2例被误诊为良性 ,误诊率较单独应用钼靶X线或超声检查 (分别有3例和9例 )显著为低 (P<0.05)。95例乳腺良性病变经联合诊断有80例明确为良性 ,7例误诊为恶性 ,与单独应用钼靶X线或超声检查比较无显著性差异 (P>0.05) ,但只有8例未明确定性 ,较单独应用钼靶X线或超声检查 (分别为25例和21例 )明显减少 (P<0.01)。结论 提示钼靶X线和超声联合诊断有助于鉴别乳腺良恶性疾病。
Objective To investigate the value of combined mammography and ultrasound in the differential diagnosis of benign and malignant breast diseases. Methods A total of 148 cases of breast diseases (including 53 cases of breast cancer and 95 cases of benign breast lesions) were diagnosed by mammographic X-ray and ultrasonography, and compared with surgical pathological diagnosis. Results 46 cases of 53 cases of breast cancer were diagnosed as malignant. The rate of diagnosis was significantly higher than that of molybdenum target X-ray or ultrasonography (only 33 cases and 29 cases respectively) (P<0.01). Only 5 cases were diagnosed by joint diagnosis. There was no clear certainty, and the uncertainty rate was significantly lower than molybdenum target X-ray or ultrasonography alone (17 and 15 cases, respectively) (P<0.05); only 2 cases were misdiagnosed as benign, and the rate of misdiagnosis was lower than that of the combined diagnosis. The use of molybdenum target X-ray or ultrasonography alone (3 and 9 cases, respectively) was significantly lower (P < 0.05). Among the 95 cases of benign breast lesions, 80 were diagnosed as benign and 7 were misdiagnosed as malignant. There was no significant difference compared with mammographic X-ray or ultrasonography alone (P>0.05), but only 8 cases were unspecified. It was significantly lower than that of molybdenum target X-ray or ultrasound examination (25 cases and 21 cases respectively) (P<0.01). Conclusions The combination of mammographic X-ray and ultrasonography can help distinguish between benign and malignant breast diseases.