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九气拈痛胶囊(丸),系药典方,有理气活血、止痛等功效,主要用于胸胁胀满疼痛、痛经等,《中国基本中成药》一部,提示本方可用于治疗慢性胃及十二指肠溃疡、慢性肠炎等消化系统病变,为证实其对消化性溃疡的治疗作用,现将3种不同剂量的九气拈痛胶囊对利血平所致的大鼠实验性胃溃疡、小鼠胃排空及小鼠小肠内炭末推进实验的方法与结果报告如下。1 实验材料1.1 药物 九气拈痛胶囊,湖南中医学院附一院药剂科提供。批号94822,胶囊内含物0.4g,相当生药量3g。九气拈痛丸(水泛丸),湖南中医学院附一院药剂科制备,批号940720(长)卫药剂(94)83-254。三九胃泰胶囊,深圳南方制药厂,批号940530,阳性对照药按100%生药含量计,功效消炎止痛,理气健胃。
Jiuqi Qutong Capsules (Pills), Department of Pharmacopoeia, has rational qi and blood circulation, pain relief and other effects, mainly for chest pain fullness pain, dysmenorrhea, etc., “Chinese basic Chinese medicine” a, suggesting that this party can be used to treat chronic stomach And duodenal ulcer, chronic enteritis and other digestive system diseases, in order to prove its therapeutic effect on peptic ulcer, now three different doses of Jiuqiqitong capsule on reserpine-induced rat experimental gastric ulcer Methods and results of mouse stomach emptying and mice’s small intestine advancement of charcoal advancement are reported below. 1 Experimental Materials 1.1 Drugs Jiuqitantong Capsule, provided by the Department of Pharmacy, First Affiliated Hospital of Hunan College of Traditional Chinese Medicine. Batch No. 94822, capsule content 0.4g, a considerable amount of crude drug 3g. Jiuqi Qutong Pill (Haipan Pill), prepared by the Department of Pharmacy, First Affiliated Hospital of Hunan College of Traditional Chinese Medicine, Lot No. 940720 (Long) Pharmacy (94) 83-254. Sanjiuweitai Capsule, Shenzhen Nanfang Pharmaceutical Factory, batch No. 940530, positive control drug is based on 100% crude drug content, the effect is anti-inflammatory and pain-relieving, and qi is good for the stomach.