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红花胺(tinctormine,TIN)是从菊科植物红花CarthamustinctoriusL.的花瓣中提取出的单体化合物,是一种有效的钙离手拈抗剂。本文旨在阐明TIN对单个心肌细胞收缩反应和钙流(Ca2+currents,Ica)抑制作用的机理。实验用单个心肌细胞取自23又体重8~12kg的成年杂种狗(雌雄均
Tetramine (TIN) is from the Compositae Carthamus tinctorius L. The monomeric compound extracted from the petals is an effective calcium antagonist. This article aims to elucidate the mechanism of inhibition of TIN on the contraction response and Ca2+ currents (Ica) of single cardiomyocytes. Experimental single cardiomyocytes were obtained from 23 adult dogs weighing 8-12 kg (male and female)