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目的 :比较西宁地区、平原地区 2型糖尿病胃轻瘫患者与健康对照组三组血浆胃动素水平与疾病相关性。方法 :选择西宁地区 2型糖尿病胃轻瘫患者 32例 ,平原地区 2型糖尿病胃轻瘫患者 2 0例及健康志愿者 2 0例 ,测定血浆胃动素水平。结果 :西宁地区糖尿病胃轻瘫患者中血浆胃动素水平 2 4例升高、5例降低、3例正常 ,平原组 15例升高、2例降低、3例正常 ,血浆胃动素水平健康组与平原及西宁地区之间、西宁与平原地区之间比较P <0 .0 1,差别有高度显著性。结论 :西宁组、平原组 2型糖尿病胃轻瘫患者血浆胃动素均高于健康对照组 ,而西宁地区组血浆胃动素低于平原组 ,考虑与中度高原地区缺氧有关。
OBJECTIVE: To compare the plasma levels of motilin and disease in three types of patients with type 2 diabetic gastroparesis and healthy controls in Xining region and plain region. Methods: Thirty-two type 2 diabetic patients with gastroparesis, 20 type 2 diabetic gastroparesis patients and 20 healthy volunteers were selected in Xining area. Plasma motilin levels were measured. Results: The levels of plasma motilin in 24 cases of diabetic gastroparesis in Xining were significantly higher than those in the control group (n = 5), normal in 3 cases, elevated in 15 cases in plain group, decreased in 2 cases, normal in 3 cases and normal in plasma motilin Between the plain and the Xining area, between Xining and the plain areas, P <0. 01, the difference was highly significant. Conclusion: Plasma motilin in patients with type 2 diabetes mellitus with gastroparesis in Xining group and plain group is higher than that in healthy control group, while plasma motilin in Xining group is lower than that in plain group, which may be related to hypoxia in moderate plateau.