中性粒细胞减少的患者发热,是常见的疑难问题。尽管血液制品、药物过敏、活动性疾病、或病毒、原虫或真菌感染均能引起发热,但往往需应用不经肠道的广谱抗生素以抑制可能发生的细菌感染。内毒素刺激后 C-反应蛋白(C-reactive protein,CRP)在24h 内从正常值(<1mg/L)迅速升高数百倍。由于其半衰期为8.9h,故其清除亦同样迅速。白细胞减少的患者,在细菌感染发生后,CRP 迅速升 People with neutropenia fever, is a common problem. Although blood products, drug allergies, active diseases, or viral, protozoal or fungal infections can cause fever, a broad spectrum of parenteral antibiotics is often used to suppress possible bacterial infections. Endotoxin stimulation C-reactive protein (C-reactive protein, CRP) increased rapidly from normal (<1mg / L) within a few hundredfold. Due to its half-life of 8.9h, its removal is equally rapid. In patients with leucopenia, CRP rapidly increases after a bacterial infection occurs