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1概述系统性小血管炎是一组自身免疫性疾病,以血管壁的炎症和纤维素样坏死为病理特征。大多数小血管炎病因不明,即原发性小血管炎;尚有部分小血管炎继发于其他因素,如结缔组织病(系统性红斑狼疮、类风湿性关节炎、干燥综合征等)并发的血管炎、药物(肼屈嗪、丙基硫氧嘧啶、可卡因、别嘌呤醇)诱发的血管炎,等。
1 Overview Systemic vasculitis is a group of autoimmune diseases, with vascular wall inflammation and fibrinoid necrosis as the pathological features. Most of the causes of small vasculitis is unknown, that is, primary small vessel vasculitis; there are still some small vasculitis secondary to other factors, such as connective tissue disease (systemic lupus erythematosus, rheumatoid arthritis, Sjogren’s syndrome, etc.) complicated Vasculitis, vasculitis induced by drugs (hydralazine, propylthiouracil, cocaine, allopurinol), and the like.