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目的探讨小儿过敏性紫癜的消化道表现,提高对本病的认识。方法对68例过敏性紫癜的临床特点及实验室检查等方面进行回顾性分析。结果发病年龄3～14岁,以消化道症状如腹痛、便血、恶心、呕吐等为首发症状35例(51.47%);以皮疹或紫癜为首发症状17例(25%);而皮疹与腹痛同时伴发者9例(13.24%)。另外,紫癜合并消化道症状及肾损害5例(7.35%);紫癜合并消化道症状及关节或下肢肿痛2例(2.94%)。所有患儿均出现皮疹和腹痛,部分患儿出现恶心、呕吐、便血或大便隐血阳性。胃镜和(或)肠镜检查8例(11.76%),主要表现为充血水肿、出血性红斑、糜烂及溃疡,病变以胃、十二指肠和回肠末端为明显。结论过敏性紫癜半数以上伴有消化道症状,内镜表现有一定特征。
Objective To investigate the gastrointestinal manifestations of Henoch-Schonlein Purpura in children and to raise awareness of the disease. Methods The clinical features and laboratory tests of 68 cases of Henoch-Schonlein purpura were retrospectively analyzed. Results The age of onset was from 3 to 14 years old. Gastrointestinal symptoms such as abdominal pain, blood in the stool, nausea and vomiting were the first symptoms in 35 cases (51.47%). The first symptom was rash or purpura in 17 cases (25%). Complications in 9 cases (13.24%). In addition, purpura with gastrointestinal symptoms and renal damage in 5 cases (7.35%); purpura with gastrointestinal symptoms and joint or lower extremity swelling and pain in 2 cases (2.94%). All children had rashes and abdominal pain, some children with nausea, vomiting, blood in the stool or fecal occult blood positive. Gastroscope and / or colonoscopy in 8 cases (11.76%), mainly manifested as congestion and edema, hemorrhagic erythema, erosion and ulcers, lesions in the stomach, duodenum and ileum as the end. Conclusion More than half of allergic purpura with gastrointestinal symptoms, endoscopic performance has certain characteristics.