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目的对照分析冠心病合并与不合并2型糖尿病患者冠状动脉造影的特点。方法对照分析2004年4月至2004年12月于阜外心血管病医院行冠状动脉造影的702例冠心病合并糖尿病患者(DM组)和702例冠心病不合并糖尿病患者(NDM组)的临床资料。冠心病定义为至少有一支主要冠状动脉或其主要分支狭窄≥50%,糖尿病诊断标准参照1999年WHO糖尿病诊断标准,用冠状动脉病变总记分(CLS)评价病变。结果①DM组高血压和高血脂的比例显著高于NDM组,DM组EF值显著低于NDM组(P均<0.05)。②DM组冠状动脉病变总记分明显高于NDM组,多支病变及弥漫性病变比例显著高于NDM组,单支病变比例显著低于NDM组(P均<0.05)。结论2型糖尿病加重冠状动脉病变程度,冠状动脉病变以多支、弥漫性病变多见。
Objective To analyze the characteristics of coronary angiography in patients with and without type 2 diabetes mellitus. Methods A total of 702 patients with coronary heart disease complicated with DM (DM group) and 702 patients with coronary heart disease without diabetes (NDM group) undergoing coronary angiography at Fu Wai Hospital from April 2004 to December 2004 were analyzed retrospectively. data. Coronary heart disease is defined as having at least one major coronary artery or stenosis of its major branches ≥50%. The diagnostic criteria for diabetes refer to the 1999 WHO diagnostic criteria for diabetes mellitus and the lesions are evaluated by the total coronary artery disease score (CLS). Results ① The proportion of hypertension and hyperlipidemia in DM group was significantly higher than that in NDM group. EF in DM group was significantly lower than that in NDM group (all P <0.05). ② The total score of coronary artery disease in DM group was significantly higher than that in NDM group. The proportion of multi-vessel disease and diffuse lesion in DM group was significantly higher than that in NDM group (P <0.05). Conclusion Type 2 diabetes aggravates the degree of coronary artery disease, multiple coronary artery disease and diffuse lesions are more common.