难治性哮喘占哮喘患者的50%至10%。虽然所占比例不高,但急诊就医频率和住院频率分别为轻中度哮喘患者的15倍和20倍,是导致哮喘治疗费用增高的重要原因之一。因此,提高难治性哮喘的诊治水平,对改善哮喘的整体控制水平和疾病预后,降低医疗成本有着重要的意义。 Refractory asthma accounts for 50% to 10% of patients with asthma. Although the proportion is not high, but the emergency medical treatment and hospitalization frequency were 15 times and 20 times of mild to moderate asthma patients, which is one of the important reasons leading to increased cost of asthma treatment. Therefore, to improve the diagnosis and treatment of refractory asthma is of great significance to improve the overall control of asthma and disease prognosis, reduce medical costs.