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目的探讨不同手术方式对长骨巨细胞瘤患者的治疗效果。方法回顾分析1995年1月~2006年12月在我院骨科行手术治疗的长骨巨细胞瘤患者113例。CampanacciⅠ级17例,Ⅱ级58例,Ⅲ级38例。行囊内刮除术87例,其中囊壁处理使用苯酚22例,无水酒精46例,50%氯化锌19例。行囊外切除术26例。平均随访时间70.2个月(24~125个月)。结果刮除组共复发23例,切除术组复发2例。刮除组不同囊壁处理方式复发率差异无显著性意义(P=0.474)。CampanacciⅢ级患者刮除术组和切除术组复发率差异有显著性意义(P=0.015)。术后MSTS评分刮除组为26.5±2.9分,优良率97.2%。切除组为23.3±4.8分,优良率为85.4%。两组评分差异有显著性意义(P=0.006)。结论长骨巨细胞瘤患者应根据影像学分级,术后功能要求等不同因素个体化选择外科治疗方式。
Objective To investigate the curative effect of different surgical methods on patients with giant cell tumor of long bone. Methods A retrospective analysis of January 1995 to December 2006 in our hospital orthopedic surgery 113 cases of giant cell tumor of the giant cell tumor. Campanacci Ⅰ grade 17 cases, Ⅱ grade 58 cases, Ⅲ grade 38 cases. 87 cases of intracapsular curettage, of which 22 cases of wall treatment using phenol, 46 cases of anhydrous alcohol, 50% zinc chloride in 19 cases. Extracapsular excision in 26 cases. The average follow-up time was 70.2 months (24 to 125 months). Results In the curettage group, 23 cases were relapsed and 2 cases in the resection group. There was no significant difference in the recurrence rate of curettage group between different wall (P = 0.474). There was a significant difference in the recurrence rate between patients with and without curettage in Campanacci class Ⅲ patients (P = 0.015). Postoperative MSTS score curettage group was 26.5 ± 2.9 points, excellent and good rate was 97.2%. The resection group was 23.3 ± 4.8, the excellent and good rate was 85.4%. There was a significant difference between the two groups (P = 0.006). Conclusion Patients with giant cell tumor of giant cell tumor should choose individualized surgical treatment according to different factors such as grading of imaging, postoperative functional requirements and so on.