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目的:评估糖尿病患者中丙型肝炎病毒感染的流行率和调查几种流行病学的和临床的因素对HCV感染的影响。设计及方法:作者将176例持续糖尿病患者与6172名供血者作比较,以公认的获得HCV感染的危险因素进行配对。使用第二代酶联免疫吸附试验(ELISA)检测血清抗-HCV。对于抗-HCV阳性标本,使用免疫印迹试验确证HCV的特异性。将这些糖尿病患者根据抗-HCV状况分成两组并分析以下各变量:年龄、性
PURPOSE: To assess the prevalence of hepatitis C virus infection in diabetic patients and to investigate the impact of several epidemiological and clinical factors on HCV infection. Design and Methods: The authors compared 176 patients with persistent diabetes to 6,172 blood donors and matched them for recognized risk factors for HCV infection. Serum anti-HCV was detected using a second-generation enzyme-linked immunosorbent assay (ELISA). For anti-HCV positive specimens, the specificity of HCV was confirmed using Western blotting. These diabetic patients were divided into two groups according to anti-HCV status and analyzed for the following variables: age, sex