作者认为,对待乙型肝炎可象控制破伤风和狂犬病一样,对于已经暴露或有持续暴露的高度危险者的最好保护方法是联合使用被动和主动免疫。本文报告接受疫苗或联合使用免疫球蛋白(HBIG)的90例受试者的免疫研究结果。他们都符合下例标准:无急、慢性肝炎史;近2个月内无HBIG接种史;血清丙氨酸转氨酶(ALT)低于45国际单位;受试的前2周,血中HBsAg、抗-HBs及抗-HBc均阴性;自愿坚持接种并按期随访 The authors argue that treating hepatitis B, like controlling tetanus and rabies, is best practiced with both passive and active immunizations for those at high risk of exposure or continuing exposure. This article reports the results of an immunization study of 90 subjects who received the vaccine or combined immunoglobulin (HBIG). They all met the following criteria: no history of acute and chronic hepatitis; history of HBIG vaccination within the last 2 months; serum alanine aminotransferase (ALT) below 45 IU; blood HBsAg, anti -HBs and anti-HBc were negative; voluntary adherence and follow-up on a regular basis