目的分析中国2009年流行性脑脊髓膜炎(流脑)发病情况及国家级监测点所在省流行病学监测和实验室监测结果,评价流脑流行现状及特征,为加强预防控制流脑暴发流行提供参考资料。方法利用国家级监测点所在省上报资料、法定传染病报告系统资料、流脑单病/专病监测信息报告管理系统资料、中国疾病预防控制中心(CDC)传染病预防控制所国家流脑实验室检测资料对2009年流脑监测结果进行分析。结果 2009年全国流脑报告发病率<0.05/10万,国家级监测点中以安徽省发病数较多(76例);<15岁儿童平均发病率为0.23/10万,儿童、学生报告病例数分别占监测省报告病例总数的42.14%和30.07%。监测省报告病例中检出A群脑膜炎奈瑟菌(Neisseria meningitidis,Nm)占23.16%,B群占4.21%,C群Nm占65.26%;健康人群中检出A群Nm占10.87%,B群Nm占28.26%,C群Nm占22.83%;健康人群A群Nm抗体阳性率平均为75.51%,C群为65.71%。结论中国流脑C群Nm检出比例逐年增多,病例最多的安徽省已成为C群流脑病例为主;健康人群带菌以B群Nm为主,C群Nm抗体阳性率明显低于A群。应针对薄弱环节,继续加强流脑监测,防止流脑暴发、流行。 Objective To analyze the epidemic situation of epidemic cerebrospinal meningitis (MCI) in China in 2009 and the epidemiological surveillance and laboratory monitoring results of the provincial-level surveillance sites in the province to evaluate the prevalence and characteristics of meningococcal meningitis. In order to strengthen the prevention and control of meningococcal outbreak Provide reference materials. Methods The data of the provincial monitoring sites, the reporting system of legal infectious diseases, the information management system of single-disease / special-purpose disease monitoring information system, the national meningitis laboratory of the Chinese Center for Disease Control and Prevention (CDC) Test data 2009 meningococcal monitoring results were analyzed. Results In 2009, the incidence of meningitis in the country was less than 0.05 / 100,000. Among the surveillance stations at the national level, there were more incidences in Anhui Province (76 cases). The average incidence rate of children under 15 years old was 0.23 / 100,000. The reported cases of children and students The number accounted for 42.14% and 30.07% of the total reported cases in the monitoring province respectively. Neisseria meningitidis group A (Nm) accounted for 23.16%, B group accounted for 4.21% and C group Nm accounted for 65.26% of the reported cases in the monitoring province; N group A accounted for 10.87% of healthy population, B The population Nm accounted for 28.26% and the population C of Nm accounted for 22.83%. The average positive rate of Nm antibody in group A was 75.51% and group C was 65.71%. Conclusion The proportion of Nm in C group of Chinese meningitis is increasing year by year. Anhui province has the most cases of C group. The prevalence of Nm antibody in C group is lower than that of A group in healthy population. Should focus on the weak links, continue to strengthen the meningitis monitoring to prevent meningitis outbreaks, epidemics.