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本文对１６名铅接触者、１４名铅中毒者和２０名非铅接触者进行了红细胞嘧啶５＇－核苷酸酶（Ｐ５Ｎ）和超氧化物歧化酶（ＳＯＤ）活性测定，并进行统计分析。结果表明铅可抑制红细胞Ｐ５Ｎ的活性，其抑制程度与铅毒效应密切相关：对照组（非接铅组）活性范围５．６～１４．２，平均１０．２μｍｏｌ尿嘧啶／ｈ／Ｈｂｇ／ｄｌ；接铅组活性范围为２．３～７．２，平均为４．４μｍｏｌ尿嘧啶／ｈ／Ｈｂｇ／ｄｌ，与非接铅组比较Ｐ＜０．００１；铅中毒组活性范围１．５～３．７，平均２．５μｍｏｌ尿嘧啶／ｈ／Ｈｂｇ／ｄｌ，与接铅组比较Ｐ＜０．００１。ＳＯＤ活性三组间无差别。
In this paper, the determination of 5-nucleotidase (P5N) and superoxide dismutase (SOD) activities of erythrocytes in 16 lead exposures, 14 lead poisoning cases and 20 non-lead exposures were performed and analyzed statistically . The results showed that lead could inhibit the activity of erythrocyte P5N and the degree of inhibition was closely related to the effect of lead poisoning: the activity of control group (non-lead group) ranged from 5.6 to 14.2 with an average of 10.2 μmol / h / Hbg / dl ; Lead group activity range of 2.3 to 7.2, with an average of 4.4μmol uracil / h / Hbg / dl, compared with non-lead group P <0.001; lead poisoning group activity range 1.5 ~ 3.7, mean 2.5 umol uracil / h / Hbg / dl, compared with the lead group P <0.001. SOD activity between the three groups no difference.