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目的:探讨新生儿疾病筛查召回重采血工作对新生儿疾病筛查质量的影响。方法:对需召回重采血新生儿进行召回原因确定,通知方法为依据召回原因和筛查情况由筛查中心直接通知,利用网络由采血单位通知,邮寄挂号信或请熟人通知;对通知召回过程中遇到的认识不足问题,采取反复讲解、多次通知方法使其能及时重采血复查,联系中断失访者做好3次以上召回追访记录,过于紧张焦虑者给予安慰劝导,对阳性病例可能性较大的召回后直接进行确诊检测。结果:2003年1月～2006年12月共计筛查92901例新生儿,需召回重采血复查确诊1779例(1.9%),实际追回重采血1354例(76.1%),阳性召回重采血率最高达96.6%,其他原因召回重采血率最高达83.6%。确诊阳性病例35例,重采血阳性率2.6%。其中高Phe6例,PKU7例,高Tsh12例,CH10例,阳性病例均出现在阳性召回中,且在1个月内得到治疗,其他原因召回中未见阳性病例,到目前为止,未发现其他原因召回中出现漏诊病例。结论:人们对于阳性召回比较重视,而对于其他原因召回不愿重新采血者,应加强新生儿疾病筛查的全面质量管理,做好宣传与培训工作,减少其他原因召回重采血。
Objective: To investigate the effect of neonatal screening and recalled blood sampling on screening quality of newborn diseases. Methods: To recall the cause of recalled re-acquisition of newborns to determine the reasons for the notification method based on the recall and screening of the situation by the screening center directly notify the use of network by the blood unit to inform, by registered mail or acquaintances to inform; informed of the recall process Encounter the problem of lack of understanding, to take repeated explanations, multiple notification methods so that it can promptly re-taken blood re-examination, contact interrupt the respondents to do more than 3 times to recall the record of follow-up, too nervous anxiety to give comfort and persuasion, positive cases The possibility of a larger recall directly after the diagnosis. Results: A total of 92 901 newborns were screened from January 2003 to December 2006. A total of 1 779 cases (1.9%) were confirmed by recalled blood sampling and 1354 cases (76.1%) were actually recovered by blood sampling. The highest rate of positive recapturing Up 96.6%, other reasons recall the highest blood up to 83.6%. 35 cases of positive diagnosis, the rate of 2.6% positive blood. Among them, there were 6 cases of high Phe, 7 cases of PKU, 12 cases of high Tsh, 10 cases of CH, and positive cases were all found in the positive recall and were treated within 1 month. No other cases of positive recall were found so far. Recalled cases of missed diagnosis. CONCLUSIONS: People pay more attention to the positive recall. For other reasons, those who do not want to recheck blood should be recalled. Total quality management of neonatal screening should be strengthened so as to promote publicity and training and reduce other reasons to recall heavy blood.