随着对甲型流感病毒结构与功能研究的深入,病毒的增殖和致病机制已逐渐被阐明。甲型流感病毒基因的UTR可变区具有片段特异性,被认为与病毒的转录、复制及包装功能密切相关。本文系统地综述甲型流感病毒UTR可变区碱基多样性与病毒的转录、复制及包装之间的关系,为研究UTR可变区碱基多态性与流感病毒重配的分子机制两者间的关系奠定基础。 With the in-depth study of the structure and function of influenza A virus, the mechanism of virus proliferation and pathogenesis has been gradually clarified. The UTR variable region of the influenza A virus gene is fragment-specific and is believed to be closely related to the transcriptional, replication and packaging functions of the virus. This article systematically reviews the relationship between the nucleotide diversity of the variable region of the influenza A virus and the transcription, replication and packaging of the virus. In order to study both the molecular mechanism of the polymorphism of the UTR variable region and the reassortment of the influenza virus The relationship between the foundation.