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鼻咽癌有多种组织学类型,但常见的仅三种,即分化差的鳞状细胞癌、未分化癌和泡状核细胞癌。这三种类型的癌细胞在电镜下虽均可见张力纤维和桥粒,都具有鳞状分化的征象,但在光镜下却是可以明确区别,而且它们的生物学特性也有所异同。这三种类型癌细胞的染色体组型有无差别?尚未见报道。我们采用细胞分光光度计测定三种不同类型癌细胞核内的DNA含量,推算出各自的染色体数目,从而对鼻咽癌的组织学分型及其生物学意义提出看法。
There are many histological types of nasopharyngeal carcinoma, but only three are common, namely poorly differentiated squamous cell carcinoma, undifferentiated carcinoma, and vesicular nucleus cell carcinoma. Although these three types of cancer cells can all see the tension fibers and desmosomes under the electron microscope, they all have the signs of squamous differentiation, but they can be clearly distinguished under the light microscope, and their biological characteristics are also similar. Is there any difference in the karyotype of these three types of cancer cells? We used a cell spectrophotometer to determine the DNA content in three different types of cancer cell nuclei and deduced the number of chromosomes so as to provide opinions on the histological type and biological significance of nasopharyngeal carcinoma.