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目的 探讨活血化淤中药方剂脑血治治疗脑出血的病理基础。方法 以兔实验性脑出血为研究对象 ,分为两组 ,对照组以常规饲料喂养 ,治疗组以鼻饲方法给予脑血治治疗。然后分别于造模后 1、2、3、5、7、10、14、2 1d取脑 ,进行系统的大体及光镜下的病理学研究。结果 发现脑血治可以促进新生毛细血管增生及血肿的吸收 ,减轻神经组织的损伤 ,治疗组的血肿吸收过程及脑组织的恢复均优于对照组 ,且无任何毒副作用。结论 脑血治可以作为一种安全有效的药物应用于脑出血的治疗 ,而活血化淤疗法作为一种新的脑出血治疗方法值得在临床推广应用。
Objective To explore the pathological basis of treatment of cerebral hemorrhage by traditional Chinese medicine for promoting blood circulation and silting. Methods Rabbit experimental cerebral hemorrhage was taken as the research object and divided into two groups. The control group was fed with conventional feed. The treatment group was treated with cerebral blood therapy by nasal feeding method. Then brains were taken at 1,2,3,5,7,10,14,21 d after modeling to perform systematic gross and light microscopy pathological studies. Results It was found that cerebral blood treatment can promote the absorption of new capillary hyperplasia and hematoma and reduce the damage of nerve tissue. The absorption of hematoma and the recovery of brain tissue in the treatment group were better than those in the control group, and there were no toxic or side effects. Conclusion Cerebral blood therapy can be used as a safe and effective drug for the treatment of cerebral hemorrhage. As a new treatment method for cerebral hemorrhage, Huoxue Huayu therapy is worthy of clinical application.