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目的探讨胸腔注射尿激酶对结核性包裹性胸膜炎的治疗效果。方法回顾性分析我院2011年2月至2014年5月间收治的结核性包裹性胸膜炎患者98例,其中49例患者抽液后注入尿激酶作为观察组,另49例患者不注入尿激酶作为对照组,比较两组患者治疗后临床疗效及抽液总量、抽液次数、胸液吸收时间、胸膜厚度情况。结果观察组治疗总有效率为93.2%,对照组为82.1%,两组比较差异有统计学意义,P<0.05;观察组治疗后抽液总量、抽液次数、胸液吸收时间、胸膜厚度与对照组比较差异有统计学意义,P<0.05。结论胸腔注射尿激酶能明显增加抽液量,减少抽液次数,缩短胸液吸收时间,临床效果较明显。
Objective To investigate the therapeutic effect of pleural injection of urokinase on tuberculous pleurisy. Methods A retrospective analysis of 98 patients with tuberculous pleurisy in our hospital from February 2011 to May 2014 was retrospectively analyzed. Among them, 49 patients were injected with urokinase as the observation group after fluid pumping and the other 49 patients were not injected with urokinase In the control group, the clinical curative effect, the total amount of fluid pumping, the frequency of pumping, the absorption time of pleural fluid and the thickness of pleural were compared between the two groups. Results The total effective rate was 93.2% in the observation group and 82.1% in the control group, the difference between the two groups was statistically significant (P <0.05). The total amount of fluid extraction, pumping times, absorption time of pleural fluid, pleural thickness Compared with the control group, the difference was statistically significant, P <0.05. Conclusion Thoracic injection of urokinase can significantly increase the amount of fluid extraction, reducing the number of pumping, shortening the absorption time of pleural fluid, the clinical effect is obvious.