扶正补虚方联合西药治疗肺癌随机平行对照研究

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[目的]观察扶正补虚方联合西药治疗肺癌疗效。[方法]使用随机平行对照方法,将70例住院患者按住院病志号法简单随机分为两组。对照组35例常规化疗:PC治疗方案,化疗前一晚22点和当日凌晨4点地塞米松0.75mg+0.09%生理盐水250m L,静滴,后紫杉醇和卡铂化疗。治疗组35例扶正补虚方(党参、茯苓、山药、熟地黄各20g,黄芪40g,当归,白芍,半夏,阿胶烊化各15g,女贞子、川贝母、枸杞子、甘草、石斛、补骨脂、沙参、生地黄、麦冬各10g,白术、陈皮各12g,肉桂3g;纳差加麦芽,神曲;肠燥加郁李仁,火麻仁),1剂/d,水煎300m L,早晚口服;化疗治疗同对照组。连续治疗7d为1疗程。观测临床症状、呕吐、骨髓抑制、骨髓白细胞、骨髓血小板、不良反应。连续治疗5疗程,判定疗效。[结果]治疗组痊愈13例,显效13例,有效6例,无效3例,总有效率91.43%。对照组痊愈6例,显效10例,有效13例,无效6例,总有效率82.86%。治疗组疗效优于对照组(P<0.05)。生存质量评分治疗组优于对照组(P<0.05)。[结论]扶正补虚方联合西药治疗肺癌效果显著,值得推广。 [Objective] To observe the therapeutic effect of Fuzheng Tixu Recipe combined with western medicine on lung cancer. [Methods] Using randomized parallel control method, 70 inpatients were randomly divided into two groups according to inpatient pathology. Control group of 35 patients with conventional chemotherapy: PC treatment, chemotherapy 22:00 the day before chemotherapy and 4:00 the same day on the same day dexamethasone 0.75mg + 0.09% saline 250ml, intravenous infusion, post-paclitaxel and carboplatin chemotherapy. The treatment group 35 cases of Fuzheng Buxu Fang (Codonopsis, Poria, yam, Rehmannia each 20g, Astragalus 40g, Angelica, white peony root, Pinellia, gelatin each of 15g, Ligustrum, Fritillaria, medlar, licorice, Dendrobium, psoralen, Radix Aconitum, Radix Rehmanniae, Ophiopogon japonicus 10g, Atractylodes, dried tangerine peel 12g, cinnamon 3g; Anadalpine plus malt, Divine Comedy; 300m L, morning and evening oral; chemotherapy with the control group. Continuous treatment 7d for a course of treatment. Observation of clinical symptoms, vomiting, myelosuppression, myeloid leukemia, bone marrow platelets, adverse reactions. Continuous treatment of 5 courses to determine the efficacy. [Results] The treatment group cured 13 cases, markedly effective in 13 cases, effective in 6 cases, 3 cases, the total effective rate was 91.43%. The control group cured 6 cases, markedly effective in 10 cases, effective in 13 cases, 6 cases, the total effective rate was 82.86%. The treatment group was better than the control group (P <0.05). The quality of life score in the treatment group was better than that in the control group (P <0.05). [Conclusion] Fuzheng Buxu Recipe combined with western medicine has significant effect on lung cancer and is worth promoting.
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