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目的观察补肾调理月经周期的方法(简称补肾调周法)联合西药治疗卵巢储备功能低下的临床疗效。方法 78例卵巢储备功能低下的患者,按随机数字表法分为中西药组(40例)和西药组(38例),西药组采用激素替代疗法,中西药组在西药治疗基础上,加用中药补肾调周法治疗,连续治疗3个月。观察两组临床疗效,比较两组治疗前后血清促卵泡激素(follicle stimulating hormone,FSH)、FSH/LH(黄体生成素luteinizing hormone,LH)、雌二醇(estradiol,E2)水平和窦卵泡发育情况。结果治疗后中西药组临床有效率(92.5%),高于西药组临床有效率(73.68%,P<0.05);与治疗前比较,治疗后两组血清FSH、FSH/LH和E2水平均降低(P<0.05),窦卵泡数量增多(P<0.05),而且在FSH、FSH/LH和窦卵泡数量方面中西药组优于西药组(P<0.05)。结论补肾调周法联合西药治疗卵巢储备功能低下优于西药组,而且在降低血清FSH、FSH/LH水平和增加窦卵泡数量方面更明显。
Objective To observe the method of tonifying the menstrual cycle (referred to as tonifying the kidney and regulating the kidney) in combination with western medicine to treat the ovarian reserve dysfunction. Methods Seventy eight patients with ovarian reserve dysfunction were divided into two groups according to the random number table: 40 cases in the Western medicine group and 38 cases in the Western medicine group. The western medicine group was treated by hormone replacement therapy. Chinese kidney Bushen Zhou treatment, continuous treatment for 3 months. The clinical efficacy of the two groups was observed. The levels of follicle stimulating hormone (FSH), FSH / LH (LH), estradiol (E2) and antral follicle development . Results After treatment, the clinical effective rate (92.5%) in Chinese and western medicine group was higher than that in western medicine group (73.68%, P <0.05). Compared with before treatment, the levels of serum FSH, FSH / LH and E2 in both groups were decreased (P <0.05). The number of antral follicles increased (P <0.05), and the number of FSH, FSH / LH and the number of antral follicles in Chinese medicine group was better than western medicine group (P <0.05). Conclusion Bushen Tiaowuji combined with Western medicine treatment of ovarian reserve is better than Western medicine group, but also in reducing serum FSH, FSH / LH levels and increase the number of antral follicles more obvious.