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目的分析应用国产封堵器介入封堵动脉导管未闭(PDA)术前后血流动力学的变化规律。方法选择2014年6月至2015年2月在我科住院的PDA患者,应用国产封堵器进行介入封堵治疗,分别于封堵术前及封堵术后测主动脉压及肺动脉压进行对比分析。结果 64例PDA患者均经导管封堵成功(技术成功率100%)。与封堵术前比较,术后肺动脉收缩压[PASP,(58±24)mmHg VS(36±11)mmHg]、肺动脉舒张压[PADP,(27±15)mmHg VS(14±6)mmHg]、平均肺动脉压[MPAP,(37±18)mmHg VS(22±6)mmHg]均显著降低(P均<0.01)。但封堵术后主动脉压升高,收缩压由(111±25)mmHg升至(126±32)mmHg(P<0.05)。结论经导管封堵PDA操作简便、技术成功率高、疗效可靠。术后肺动脉压明显下降。
Objective To analyze the changes of hemodynamics before and after the occlusion of patent ductus arteriosus (PDA) by domestic occluder. Methods PDA patients hospitalized in our department from June 2014 to February 2015 were enrolled in this study. The domestic occluder was used for the interventional occlusion treatment. The aortic pressure and pulmonary arterial pressure were measured before and after closure, respectively analysis. Results All 64 PDA patients were successfully treated with catheterization (technical success rate 100%). Compared with preoperative closure, pulmonary artery systolic pressure (PASP, (58 ± 24) mmHg VS (36 ± 11) mmHg], pulmonary artery diastolic pressure [PADP, (27 ± 15) mmHg VS (14 ± 6) mmHg] , Mean pulmonary arterial pressure (MPAP, (37 ± 18) mmHg vs (22 ± 6) mmHg) were significantly lower (all P <0.01). However, the aortic pressure increased after closure and systolic blood pressure increased from (111 ± 25) mmHg to (126 ± 32) mmHg (P <0.05). Conclusions Transcatheter closure of PDA is easy to operate and has high technical success rate and reliable curative effect. Postoperative pulmonary artery pressure decreased significantly.